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1

Molecular biology of the 5-HT1 receptor subfamily

Dr. Paul R. Hartig, Nika Adham, John Zgombick, Richard Weinshank, Theresa Branchek

Journal:

Drug Development Research

Year:

1992

Language:

english

File:

PDF, 608 KB

english, 1992

2

ChemInform Abstract: N-Methyl-5-tert-butyltryptamine: A Novel, Highly Potent 5-HT1D Receptor Agonist.

Yao-Chang Xu, John M. Schaus, Clint Walker, Joe Krushinski, Nika Adham, John M. Zgombick, Sidney X. Liang, Dan T. Kohlman, James E. Audia

Journal:

Year:

1999

File:

PDF, 34 KB

1999

3

Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT1F receptor agonists

Brian M. Mathes, Kevin J. Hudziak, John M. Schaus, Yao-Chang Xu, David L. Nelson, David B. Wainscott, Suzanne E. Nutter, Wendy H. Gough, Theresa A. Branchek, John M. Zgombick, Sandra A. Filla

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

4

Privileged structure based ligands for melanocortin-4 receptors—Aliphatic piperazine derivatives

Karin Briner, Iván Collado, Matthew J. Fisher, Cristina García-Paredes, Saba Husain, Steven L. Kuklish, Ana I. Mateo, Thomas P. O’Brien, Paul L. Ornstein, John Zgombick, Óscar de Frutos

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

5

Privileged structure based ligands for melanocortin receptors—4,4-Disubstituted piperidine derivatives

Steven L. Kuklish, Ryan T. Backer, Karin Briner, Christopher W. Doecke, Saba Husain, Jeffrey T. Mullaney, Paul L. Ornstein, John M. Zgombick, Thomas P. O’Brien, Matthew J. Fisher

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 117 KB

english, 2006

6

Pharmacological characterizations of recombinant human 5-HT1D1Dαand 5-HT1Dβreceptor subtypes coupled to adenylate cyclase inhibition in clonal cell lines: apparent differences in drug intrinsic efficacies between human 5-HT1Dsubtypes

John M. Zgombick, Lee E. Schechter, Nika Adham, Stefan A. Kucharewicz, Richard L. Weinshank, Theresa A. Branchek

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.27 MB

english, 1996

7

Differences in ligand binding profiles between cloned rabbit and human 5-HT1Dαand 5-HT1Dβreceptors: ketanserin and methiothepin distinguish rabbit 5-HT1Dreceptor subtypes

Jonathan A. Bard, Stefan A. Kucharewicz, John M. Zgombick, Richard L. Weinshank, Theresa A. Branchek, Marlene L. Cohen

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1996

Language:

english

File:

PDF, 929 KB

english, 1996

8

Native 5-HT1B receptors expressed in OK cells display dual coupling to elevation of intracellular calcium concentrations and inhibition of adenylate cyclase

J. M. Zgombick, Theresa A. Branchek

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1998

Language:

english

File:

PDF, 115 KB

english, 1998

9

[3H]LY334370, a novel radioligand for the 5-HT1Freceptor. I. In vitro characterization of binding properties

David B. Wainscott, Joseph H. Krushinski, James E. Audia, John M. Schaus, John M. Zgombick, Virginia L. Lucaites, David L. Nelson

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

10

Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines

Matthew J. Fisher, Ryan T. Backer, Saba Husain, Hansen M. Hsiung, Jeffrey T. Mullaney, Thomas P. O’Brian, Paul L. Ornstein, Roger R. Rothhaar, John M. Zgombick, Karin Briner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

11

Effects of nicotine on β-endorphin, αMSH, and ACTH secretion by isolated perfused mouse brains and pituitary glands, in Vitro

M.A. Marty, V.G. Erwin, K. Cornell, J.M. Zgombick

Journal:

Pharmacology Biochemistry and Behavior

Year:

1985

Language:

english

File:

PDF, 671 KB

english, 1985

12

Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes

John M. Zgombick, Lee E. Schechter, Stefan A. Kucharewicz, Richard L. Weinshank, Theresa A. Branchek

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1995

Language:

english

File:

PDF, 644 KB

english, 1995

13

A receptor autoradiographic and in situ hybridization analysis of the distribution of the 5-ht7 receptor in rat brain

Eric L. Gustafson, Margaret M. Durkin, Jonathan A. Bard, John Zgombick, Theresa A. Branchek

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 3.05 MB

english, 1996

14

Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: Binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine

Lee A. Phebus, Kirk W. Johnson, John M. Zgombick, Pierre J. Gilbert, Kristel Van Belle, Vincent Mancuso, David L.G. Nelson, David O. Calligaro, Anton D. Kiefer Jr., Theresa A. Branchek, Michael E. Fla

Journal:

Year:

1997

Language:

english

File:

PDF, 687 KB

english, 1997

15

Cloning and Characterization of The Guinea Pig 5-HT1F Receptor Subtype: a Comparison of the Pharmacological Profile to the Human Species Homolog

N ADHAM, J.A BARD, J.M ZGOMBICK, M.M DURKIN, S KUCHAREWICZ, R.L WEINSHANK, T.A BRANCHEK

Journal:

Neuropharmacology

Year:

1997

Language:

english

File:

PDF, 2.00 MB

english, 1997

16

Molecular Cloning and Pharmacological Characterization of Guinea Pig 5-HT1B and 5-HT1D Receptors

J.M ZGOMBICK, J.A BARD, S.A KUCHAREWICZ, D.A URQUHART, R.L WEINSHANK, T.A BRANCHEK

Journal:

Neuropharmacology

Year:

1997

Language:

english

File:

PDF, 2.89 MB

english, 1997

17

Novel Potent 5-HT 1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N -[3-(1-Methyl-4-piperidinyl)-1 H -pyrrolo[3,2- b ]pyridin-5-yl]amides §

Filla, Sandra A., Mathes, Brian M., Johnson, Kirk W., Phebus, Lee A., Cohen, Marlene L., Nelson, David L., Zgombick, John M., Erickson, Jon A., Schenck, Kathryn W., Wainscott, David B., Branchek, Ther

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 197 KB

english, 2003

18

Ethanol differentially enhances adrenocortical response in LS and SS mice

Zgombick, John M., Erwin, V.Gene

Journal:

Year:

1988

Language:

english

File:

PDF, 805 KB

english, 1988

19

N -Methyl-5- tert -butyltryptamine: A Novel, Highly Potent 5-HT 1D Receptor Agonist

Xu, Yao-Chang, Schaus, John M., Walker, Clint, Krushinski, Joe, Adham, Nika, Zgombick, John M., Liang, Sidney X., Kohlman, Dan T., Audia, James E.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

20

Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.

Weinshank, R. L., Zgombick, J. M., Macchi, M. J., Branchek, T. A., Hartig, P. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.33 MB

english, 1992

21

Human Serotonin 1D Receptor is Encoded by a Subfamily of Two Distinct Genes: 5-HT1Dαand 5-HT1Dβ

Richard L. Weinshank, John M. Zgombick, Mary J. Macchi, Theresa A. Branchek and Paul R. Hartig

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

22

5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs

Johnson, Kirk W., Schaus, John M., Durkin, Margaret M., Audia, James E., Kaldor, Stephen W., Flaugh, Michael E., Adham, Nika, Zgombick, John M., Cohen, Marlene L., Branchek, Theresa A., Phebus, Lee A.

Journal:

Year:

1997

Language:

english

File:

PDF, 400 KB

english, 1997

23

Central Mechanisms of Ethanol-Induced Adrenocortical Response in Selectively Bred Lines of Mice

Zgombick, John M., Erwin, Gene

Journal:

Neuroendocrinology

Year:

1987

Language:

english

File:

PDF, 1.38 MB

english, 1987

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